Hormone replacement therapy can help with weight loss by replenishing hormones that decline with age, such as testosterone or thyroid hormones. Diet modification involves reducing calorie intake and increasing the consumption of nutrient-dense foods to induce weight loss.

Circadian rhythm is the body’s internal clock that regulates sleep and metabolism, and disruption of this rhythm can lead to weight gain. Optimizing circadian rhythm by establishing regular sleep patterns and meal times can help with weight loss.

Intermittent fasting involves alternating periods of eating and fasting to induce weight loss. This approach can improve insulin sensitivity and increase fat burning.

Peptides are amino acid chains that can influence body composition, including fat loss and muscle gain. Certain peptides can also increase metabolism and suppress appetite.

Naltrexone is a medication used to treat addiction, but research suggests it can also aid in weight loss by suppressing appetite and reducing food cravings. When used in combination with diet and lifestyle modifications, hormone replacement therapy, circadian rhythm optimization, intermittent fasting, peptides, and naltrexone can be effective tools to achieve sustained weight loss.